ResIn is recruiting a research fellow! See our latest post for more information, closing date for applications is 27 August.
Research Investments in Global Health (ResIn) is an analysis of investments in infectious disease research.

wordcloud diseasesOur work so far has concentrated on collating information on funded studies from all the major public and philanthropic funders of UK biomedical research and analysing these awards to UK institutions for infectious disease research over the time period of 1997 to 2013. We have and continue to publish the study findings in numerous peer-reviewed publications. Presentations and downloads of the data can be filtered and customised through the online open-access database. We have also commenced similar analyses in oncology research. Further, we are also collecting information on funding awarded to US institutions for infectious disease, plus preliminary work on research funding for an oncology dataset.

In 2015, we have also been awarded funding from the Bill & Melinda Gates Foundation to greatly expand our work!


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Recent updates

  • ResIn is recruiting!

  • The Research Investments in Global Health study is recruiting!

    Research Fellow in infectious disease research investment analyses
    Location:  Southampton General Hospital
    Salary:   £28,695 to £35,256
    Full Time Fixed Term
    Closing Date:   Friday 28 August 2015


    We wish to appoint a (non-laboratory) Research Fellow in infectious disease research investment analyses. The ResIn team (as of October 2015) will be led by Dr Stuart Clarke and based within the University of Southampton at Southampton General Hospital. The project has been awarded funding from the Bill & Melinda Gates Foundation to collate funding data from the G20 countries relating to infectious diseases (in particular pneumonia and neonatal infection research) and to assess how much funding is awarded to each disease area, how well investment correlates with the burden of disease and to measure the impact and outputs of research.

    This post provides an exciting opportunity for someone with an interest in infectious disease research. It will also be of interest to those who would enjoy building tools and analyses that will be useful in informing the decisions and priority-setting of high-ranking policymakers (e.g. the World Health Organisation), the world’s leading biomedical and health research funders, and individual research institutions, groups and societies and researchers.

    Applications are invited from those with an interest in infectious diseases, health policy or disease burden measurement. Relevant experience of a systematic and detailed approach to carrying out research projects is essential.

    Click here for more information and to apply.


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  • ResIn receives funding from the Bill & Melinda Gates Foundation!

  • We are delighted to announce that the Research Investments in Global Health study has received funding from the Bill & Melinda Gates Foundation for a two year study. The award is for $586k (approximately £378k) and will expand on the UK analyses, and investigate infectious disease research investments (in particular pneumonia, and maternal & neonatal infections) across the G20 countries. We will continue to assess investment against metrics of the global and national burdens of disease, and we will also measure research outputs and the impact of research. The study will be based at the University of Southampton and led by Dr Stuart Clarke.

    Pneumonia and maternal and neonatal infectious diseases (such as influenza, tetanus and respiratory syncytial virus) have been cited as priority areas by both the World Health Organisation (WHO) and the Gates Foundation. The 2013 Global Burden of Disease study estimated there to be 800,000 pneumonia deaths annually worldwide and the disease continues to be the number one infectious killer of children under the age of five, with more deaths than HIV, TB and malaria combined. This is despite the existence of lifesaving treatments and prevention measures, such as effective vaccines.

    “The high disease burden, particularly amongst young and elderly populations in poor to middle income countries, could potentially be addressed by further investment in research,” says Dr Stuart Clarke from the University of Southampton’s Faculty of Medicine, who is leading the study.

    “We will quantify the contribution of research funds that these infections receive compared to research involving other pathogens that are important in human health. This will give policy makers a comprehensive picture of where there’s been a lack of funding relative to the impact of the disease and help to set global research investment priorities,” Dr Clarke adds.

    Based within the University’s Faculty of Medicine, the study also contributes to the Global Health Research Institute, headed by co-applicant Professor Marie-Louise Newell (also of Southampton). The findings will be compiled in an open-access database, creating a wealth of information for all funders, policymakers and researchers to view and apply to their own work.

    Co-applicant and senior research fellow, Michael Head explains: “The database will allow funders to identify existing research in areas of mutual interest, help researchers identify collaborators, expertise and infrastructure, and support high-level policymakers (such as the WHO R&D Observatory) to identify funding trends and the relative value of investments in their areas of interest.”

    The two year study will start in October 2015.

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  • ‘Funding for infectious disease institutions’ paper published in JRSM Open

  • The latest publication to come out of the Research Investments in Global Health study is published today in JRSM Open. It covers the institutions that receive the funding and shows how for some disease areas, there are clear centres of excellence and some clear gaps in their portfolios.

    The abstract is below, and see the full open access paper at the JRSM Open website.

    Systematic analysis of funding awarded to inst
    itutions in the United Kingdom for infectious disease research, 1997–2010

    Objectives This study aimed to assess the research investments made to UK institutions for all infectious disease research and identify the direction of spend by institution.

    Design Systematic analysis. Databases and websites were systematically searched for information on relevant studies funded for the period 1997–2010.

    Setting UK institutions carrying out infectious disease research.

    Participants None.

    Main outcome measures Twenty academic institutions receiving greatest sum investments across infection are included here, also NHS sites, Sanger Institute, Health Protection Agency and the Medical Research Council. We measured total funding, median award size, disease areas and position of research along the R&D value chain.

    Results Included institutions accounted for £2.1 billion across 5003 studies. Imperial College and University of Oxford received the most investment. Imperial College led the most studies. The Liverpool and London Schools of Tropical Medicine had highest median award size, whereas the NHS sites combined had many smaller studies. Sum NHS funding appears to be declining over time, whilst university income is relatively stable. Several institutions concentrate almost exclusively on pre-clinical research. In some areas, there is clearly a leading institution, e.g. Aberdeen and mycology research or UCL and antimicrobial resistance.

    Conclusion UK institutions carry out research across a wide range of infectious disease areas. This analysis can identify centres of excellence and help inform future resource allocation for research priorities. Institutions can use this analysis for establishing expertise within their groups, identifying external collaborators and informing local research strategy.

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